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OthersAcquired thrombophilia
About thrombosis
Thrombophilia: congenital thrombophilia
Other congenital thrombophilias
There are a few other rare conditions that are associated with venous thrombosis. These include Dysfibrinogenaemia.
Dysfibrinogenaemia
Individuals with Dysfibrinogenaemia have an abnormal fibrinogen molecule in
the blood. Some people with this condition have a tendency to bleed more,
others have a tendency to thrombosis, and some have both.
Inheritance
Dysfibrinogenaemia is inherited in an autosomal
dominant way. This means that if one parent has it, there is a 50:50 chance
(1 in 2) that a child will inherit it.
Dysfibrinogenaemia and venous thrombosis
The risk of venous thrombosis depends on the type of dysfibrinogenaemia.
The risk of venous thrombosis increases when one or more additional risk factors are present.
This risk can be reduced through prevention.
Preventing venous thrombosis
People who have dysfibrinogenaemia can reduce
the risk of venous thrombosis by making lifestyle changes, such as:
- Leading a physically active life
- Eating a healthy, balanced diet
- Avoiding becoming overweight or obese
- Avoiding long periods of immobility during illness
or when travelling - Stopping cigarette smoking
Individuals with dysfibrinogenaemia should also seek medical advice before major surgery, or when they are likely to be immobile for a long period, as this increases the risk of venous thrombosis.
Women with dysfibrinogenaemia should seek medical advice before taking oral contraception or hormone replacement therapy, and when pregnant or planning to become pregnant.
Dysfibrinogenaemia and pregnancy
It is important that women with dysfibrinogenaemia who are pregnant discuss
this with their obstetrician, as they are at increased risk of venous thrombosis
during pregnancy.
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