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About thrombosis
Venous thrombosis

Risk factors for venous thrombosis

The main risk factors for venous thrombosis include:

  • Increasing age
  • Immobility
  • Heart attack or stroke
  • A recent operation especially on hips or knees
  • Previous deep vein thrombosis
  • Previous deep vein thrombosis in the family
  • Cancer and its treatment
  • Pregnancy
  • The use of the combined oral contraceptive pill and hormone replacement therapy
  • Long-distance travel
  • Known thrombophilia

When an individual has a venous thrombosis, it is usually because more than one risk factor is present at any one time. This is known as the multi-hit hypothesis.

For example, someone may have been born with a congenital thrombophilia, but will not have a thrombosis unless other risk factors are present, which increase the risk.

Download our fact sheet on preventing venous thromboembolism in hospital (pdf format)

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Long distance travel increases risk of DVT

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